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  • Featured Product
  • KD/KO Validated

EPHX2 Monoclonal antibody, PBS Only

EPHX2 Monoclonal Antibody for WB,Indirect ELISA,IHC

Host / Isotype

Mouse / IgG2b

Reactivity

Human, Pig

Applications

WB,Indirect ELISA,IHC

Conjugate

Unconjugated

CloneNo.

4H6C8

Cat No : 67322-1-PBS

Print datasheet

Synonyms

CEH, Cytosolic epoxide hydrolase, EPHX2, Epoxide hydratase, Epoxide hydrolase 2, SEH, Soluble epoxide hydrolase

验证数据展示

  • WB analysis using 67322-1-Ig (same clone as 67322-1-PBS)

    WB analysis using 67322-1-Ig (same clone as 67322-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67322-1-Ig (EPHX2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67322-1-PBS in a different storage buffer formulation.

  • WB analysis of A549 using 67322-1-Ig (same clone as 67322-1-PBS)

    WB analysis of A549 using 67322-1-Ig (same clone as 67322-1-PBS)

    WB result of EPHX2 antibody (67322-1-Ig; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-EPHX2 transfected A549 cells. This data was developed using the same antibody clone with 67322-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 67322-1-Ig (same clone as 67322-1-PBS)

    IHC staining of human breast cancer using 67322-1-Ig (same clone as 67322-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67322-1-Ig (EPHX2 antibody) at dilution of 1:4000 (under 10x lens). This data was developed using the same antibody clone with 67322-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with EPHX2 antibody included
  • IHC staining of human breast cancer using 67322-1-Ig (same clone as 67322-1-PBS)

    IHC staining of human breast cancer using 67322-1-Ig (same clone as 67322-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67322-1-Ig (EPHX2 antibody) at dilution of 1:4000 (under 40x lens). This data was developed using the same antibody clone with 67322-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with EPHX2 antibody included
Planning an IHC experiment? We recommend our IHCeasy EPHX2 Ready-To-Use IHC Kit. EPHX2 primary antibody included.

产品信息

67322-1-PBS targets EPHX2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Pig samples.

Tested Applications WB,Indirect ELISA,IHC Application Description
Tested Reactivity Human, Pig
Immunogen EPHX2 fusion protein Ag4870 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name epoxide hydrolase 2, cytoplasmic
Synonyms CEH, Cytosolic epoxide hydrolase, EPHX2, Epoxide hydratase, Epoxide hydrolase 2, SEH, Soluble epoxide hydrolase
Calculated Molecular Weight 63 kDa
Observed Molecular Weight 56-63 kDa
GenBank Accession NumberBC013874
Gene Symbol EPHX2
Gene ID (NCBI) 2053
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP34913
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

EPHX2(Epoxide hydrolase 2) acts on epoxides (alkene oxides, oxiranes) and arene oxides and plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. A number of single nucleotide polymorphisms (SNPs) in human EPHX2 have been linked to cardiovascular disease risk, including increased risk of coronary heart disease, hyperlipoproteinemia, and type-2 diabetes (PMID: 14732757, 16595607, 14673705, 15845398, 17460077). It was observed in many tissues with the band of 63 kDa in the western blot. It has also been reported that the N-terminal domain might promote dimerization of EPHX2 (PMID:21553642).