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ERCC5 Monoclonal antibody, PBS Only

ERCC5 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G2C9

Cat no : 67055-1-PBS

Print datasheet

Synonyms

COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC

验证数据展示

  • WB analysis using 67055-1-Ig (same clone as 67055-1-PBS)

    WB analysis using 67055-1-Ig (same clone as 67055-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67055-1-Ig (ERCC5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67055-1-PBS in a different storage buffer formulation.

产品信息

67055-1-PBS targets ERCC5 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen ERCC5 fusion protein Ag28561 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name excision repair cross-complementing rodent repair deficiency, complementation group 5
Synonyms COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC
Calculated Molecular Weight 1186 aa, 133 kDa
Observed Molecular Weight 200 kDa
GenBank Accession NumberBC031522
Gene Symbol ERCC5
Gene ID (NCBI) 2073
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP28715
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair (NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677]. The calculated molecular weight of ERCC5 is 133 kDa, but the modified ERCC5 protein is about 200 kDa.