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验证数据展示

  • WB analysis of mouse brain using 20548-1-AP

    WB analysis of mouse brain using 20548-1-AP

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 20548-1-AP (ERCC6/CSB antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

ERCC6/CSB Polyclonal antibody

ERCC6/CSB Polyclonal Antibody for WB, ELISA
Cat No. 20548-1-AP

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

ARMD5, ATP dependent helicase ERCC6, CKN2, Cockayne syndrome protein CSB, COFS, COFS1, CSB, ERCC6, RAD26

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size: 

-/ -

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经过测试的应用

Positive WB detected inmouse brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

20548-1-AP targets ERCC6/CSB in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms ARMD5, ATP dependent helicase ERCC6, CKN2, Cockayne syndrome protein CSB, COFS, COFS1, CSB, ERCC6, RAD26
Calculated Molecular Weight 168 kDa
Observed Molecular Weight 150 kDa
GenBank Accession NumberNM_000124
Gene Symbol ERCC6/CSB
Gene ID (NCBI) 2074
RRIDAB_10732961
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP0DP91
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ERCC6, also named as CSB, belongs to the SNF2/RAD54 helicase family. It is involved in the preferential repair of active genes. It is presumed DNA or RNA unwinding function. ERCC6 corrects the UV survival and RNA synthesis after UV exposure of Cockayne syndrome complementation group B. Defects in ERCC6 are the cause of Cockayne syndrome type B (CSB) , cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DSC), and UV-sensitive syndrome (UVS). Genetic variation in ERCC6 is associated with susceptibility to age-related macular degeneration type 5 (ARMD5). The antibody is specific to ERCC6.

实验方案

Product Specific Protocols
WB protocol for ERCC6/CSB antibody 20548-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols