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ERMN Monoclonal antibody, PBS Only

ERMN Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, mouse, rat, pig

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B1C1

Cat no : 66605-1-PBS

Print datasheet

Synonyms

ermin, ermin, ERM like protein, ERMN, JN, Juxtanodin, KIAA1189

验证数据展示

  • WB analysis using 66605-1-Ig (same clone as 66605-1-PBS)

    WB analysis using 66605-1-Ig (same clone as 66605-1-PBS)

    Various tissues were subjected to SDS PAGE followed by western blot with 66605-1-Ig (ERMN antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66605-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66605-1-Ig (same clone as 66605-1-PBS)

    IHC staining of mouse brain using 66605-1-Ig (same clone as 66605-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66605-1-Ig (ERMN antibody) at dilution of 1:300 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66605-1-PBS in a different storage buffer formulation.

产品信息

66605-1-PBS targets ERMN in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, pig
Immunogen ERMN fusion protein Ag27040 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name ermin, ERM-like protein
Synonyms ermin, ermin, ERM like protein, ERMN, JN, Juxtanodin, KIAA1189
Observed Molecular Weight 50 kDa
GenBank Accession NumberBC026345
Gene Symbol ERMN
Gene ID (NCBI) 57471
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8TAM6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ERMN is associated with cytoskeletal rearrangements and the stability of myelin sheath. A study has shown that ERMN is expressed specifically in oligodendrocytes in the central nervous system (CNS), and is involved in the formation of myelin (PMID: 20934411). The predicted MW of ERMN is 33 KDa, while western blot analyses of different tissue lysates using 66605-1-Ig antibody to ERMN detected a 50 kDa single band protein as a result of phosphorylation modification.