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ESR2 Beta 3 Polyclonal antibody, PBS Only

ESR2 Beta 3 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 55441-1-PBS

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Synonyms

验证数据展示

  • IF Staining of HeLa using 55441-1-AP (same clone as 55441-1-PBS)

    IF Staining of HeLa using 55441-1-AP (same clone as 55441-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using ESR2 Beta 3 antibody (55441-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red) DAPI (blue). This data was developed using the same antibody clone with 55441-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervix using 55441-1-AP (same clone as 55441-1-PBS)

    IHC staining of human cervix using 55441-1-AP (same clone as 55441-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervix using 55441-1-AP (ESR2 Beta-3 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 55441-1-PBS in a different storage buffer formulation.

产品信息

55441-1-PBS targets ESR2 Beta 3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name estrogen receptor 2 (ER beta)
Synonyms
Calculated Molecular Weight 58 kDa
GenBank Accession NumberNM_001437
Gene Symbol ESR2
Gene ID (NCBI) 2100
RRIDAB_2881334
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ92731
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Estrogen receptor-beta (ESR2) is a member of the superfamily of nuclear receptors, which can transduce extracellular signals into transcriptional responses. It binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual