• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of rat brain using 11690-1-AP (same clone as 11690-1-PBS)

    WB analysis of rat brain using 11690-1-AP (same clone as 11690-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 11690-1-AP (EXOC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11690-1-PBS in a different storage buffer formulation.

  • IHC staining of human gliomas using 11690-1-AP (same clone as 11690-1-PBS)

    IHC staining of human gliomas using 11690-1-AP (same clone as 11690-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas using 11690-1-AP (EXOC1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11690-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 11690-1-AP (same clone as 11690-1-PBS)

    IP experiment of mouse brain using 11690-1-AP (same clone as 11690-1-PBS)

    IP result of anti-EXOC1 (IP:11690-1-AP, 3ug; Detection:11690-1-AP 1:1000) with mouse brain tissue lysate 3600ug. This data was developed using the same antibody clone with 11690-1-PBS in a different storage buffer formulation.

  • IF Staining of human placenta using 11690-1-AP (same clone as 11690-1-PBS)

    IF Staining of human placenta using 11690-1-AP (same clone as 11690-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human placenta tissue using EXOC1 antibody (11690-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11690-1-PBS in a different storage buffer formulation.

  • IF Staining of C2C12 using 11690-1-AP (same clone as 11690-1-PBS)

    IF Staining of C2C12 using 11690-1-AP (same clone as 11690-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed C2C12 cells using EXOC1 antibody (11690-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 11690-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

EXOC1 Polyclonal antibody, PBS Only

EXOC1 Polyclonal Antibody for WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA
Cat No. 11690-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

11690-1-PBS targets EXOC1 in WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 EXOC1 fusion protein Ag2303 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 exocyst complex component 1
别名
计算分子量 894 aa, 102 kDa
观测分子量 102 kDa
GenBank蛋白编号BC020650
基因名称 EXOC1
Gene ID (NCBI) 55763
RRIDAB_2231500
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NV70
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EXOC1 (exocyst complex component 1), also known as SEC3, is a component of the exocyst complex which is essential for the targeting of exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex is an octameric complex that tethers vesicles at the plasma membrane, regulates polarized exocytosis, and recruits membranes and proteins required for nanotube formation.Recently it has been reported that exocyst complex proteins are likely a key effector of Nef-mediated enhancement of nanotube formation, and possibly microvesicle secretion, which suggests a new paradigm of exocyst involvement in polarized targeting for intercellular transfer of viral proteins and viruses.