Endoglin/CD105 Recombinant antibody
Endoglin/CD105 Uni-rAbTM Recombinant Antibody for IF/ICC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
230047E8
验证数据展示
经过测试的应用
Positive IF/ICC detected in | HUVEC cells |
Planning an IHC experiment? We recommend our IHCeasy CD105 Ready-To-Use IHC Kit. CD105 primary antibody included.
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)/ICC | IF/ICC : 1:125-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
The immunogen of 82993-5-RR is Endoglin/CD105 Fusion Protein expressed in E. coli.
Tested Applications | IF/ICC, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | Fusion Protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | endoglin |
Synonyms | CD105, END, Endoglin, ENG, HHT1, ORW, ORW1, 230047E8 |
Calculated Molecular Weight | 71 kDa |
GenBank Accession Number | BC014271 |
Gene Symbol | CD105 |
Gene ID (NCBI) | 2022 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P17813 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)
实验方案
Product Specific Protocols | |
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IF protocol for Endoglin/CD105 antibody 82993-5-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |