F4/80 Polyclonal antibody
F4/80 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse and More (1)
Applications
ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy Mouse F4/80 Ready-To-Use IHC Kit. Mouse F4/80 primary antibody included.
发表文章中的应用
| WB | See 3 publications below |
| IHC | See 17 publications below |
产品信息
18705-1-AP targets F4/80 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB, IHC |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse, rat |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 |
| Synonyms | DD7A5 7, EGF TM7, Emr1, F4 80, F4/80, Gpf480, Ly71, TM7LN3 |
| Calculated Molecular Weight | 102 kDa |
| GenBank Accession Number | BC075688 |
| Gene Symbol | F4/80 |
| Gene ID (NCBI) | 13733 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q61549 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Mouse F4/80, also named as EMR1 and Gpf480, is a 160kd cell surface glycoprotein which is a member of the EGF TM7 family. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria and Langerhans cells in the skin. The function of F4/80 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration or as a G protein-coupled signaling component of macrophages.
发表文章
| Species | Application | Title |
|---|---|---|
EMBO J Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma. | ||
J Am Soc Nephrol Targeted Deletion of p53 in the Proximal Tubule Prevents Ischemic Renal Injury. | ||
Aging (Albany NY) Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition. | ||
Oncotarget Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation. | ||
Clin Sci (Lond) G-CSF partially mediates bone loss induced by Staphylococcus aureus infection in mice. | ||
Sci Rep New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats. |