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  • Featured Product
  • KD/KO Validated

FABP4 Polyclonal antibody, PBS Only

FABP4 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12802-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 12802-1-AP (same clone as 12802-1-PBS)

    WB analysis using 12802-1-AP (same clone as 12802-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12802-1-AP (FABP4 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12802-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brown adipose using 12802-1-AP (same clone as 12802-1-PBS)

    IHC staining of rat brown adipose using 12802-1-AP (same clone as 12802-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brown adipose slide using 12802-1-AP (FABP4 antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12802-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FABP4/AP2 antibody included
  • IHC staining of rat brown adipose using 12802-1-AP (same clone as 12802-1-PBS)

    IHC staining of rat brown adipose using 12802-1-AP (same clone as 12802-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brown adipose slide using 12802-1-AP (FABP4 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12802-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FABP4/AP2 antibody included
  • IHC staining of mouse skin using 12802-1-AP (same clone as 12802-1-PBS)

    IHC staining of mouse skin using 12802-1-AP (same clone as 12802-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 12802-1-AP (FABP4 antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12802-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FABP4/AP2 antibody included
  • IHC staining of mouse skin using 12802-1-AP (same clone as 12802-1-PBS)

    IHC staining of mouse skin using 12802-1-AP (same clone as 12802-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 12802-1-AP (FABP4 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12802-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FABP4/AP2 antibody included
Planning an IHC experiment? We recommend our IHCeasy FABP4/AP2 Ready-To-Use IHC Kit. FABP4/AP2 primary antibody included.

产品信息

12802-1-PBS targets FABP4 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen FABP4 fusion protein Ag3912 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name fatty acid binding protein 4, adipocyte
Synonyms
Calculated Molecular Weight 132 aa, 15 kDa
Observed Molecular Weight 15 kDa
GenBank Accession NumberBC003672
Gene Symbol FABP4
Gene ID (NCBI) 2167
RRIDAB_2102442
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP15090
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fatty acid binding protein (FABP) 4 is a member of the FABP family which abundantly expressed, fatty acid carrier proteins. FABPs are capable of binding a variety of hydrophobic molecules such as long-chain fatty acids and are important for their uptake and intracellular trafficking. It was first identified as an adipocyte-specific protein, important for the maintenance of lipid and glucose metabolism. It is also detected in macrophages, where it participates in regulating inflammation and cholesterol trafficking via NFκB and PPAR. In more recent studies, FABP4 has been found in a variety of endothelial cells, where it has been identified as a target of VEGF and a regulator of cell proliferation and possibly angiogenesis. Pathologically, FABP4 has been associated with the development of metabolic syndrome, diabetes and cancer and vulnerability of atherosclerotic plaques. FABP4 has been identified as a novel prognostic factor for both adverse cardiovascular events and breast cancer.