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FBXO32 Recombinant antibody, PBS Only

FBXO32 Recombinant Antibody for IF, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

IF, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230243H7

Cat No : 82941-1-PBS

Print datasheet

Synonyms

Atrogin 1, F box only protein 32, F box protein 32, Fbx32, FBXO32, FLJ32424, MAFbx, Muscle atrophy F box protein

验证数据展示

  • IF Staining of C2C12 using 82941-1-RR (same clone as 82941-1-PBS)

    IF Staining of C2C12 using 82941-1-RR (same clone as 82941-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed C2C12 cells using FBXO32 antibody (82941-1-RR, Clone: 230243H7 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 82941-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy FBXO32 Ready-To-Use IHC Kit. FBXO32 primary antibody included.

产品信息

82941-1-PBS targets FBXO32 in IF, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications IF, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen FBXO32 fusion protein Ag29394 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name F-box protein 32
Synonyms Atrogin 1, F box only protein 32, F box protein 32, Fbx32, FBXO32, FLJ32424, MAFbx, Muscle atrophy F box protein
Calculated Molecular Weight 355 aa, 42 kDa
GenBank Accession NumberBC024030
Gene Symbol FBXO32
Gene ID (NCBI) 114907
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ969P5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

FBXO32 (F box only protein 32), also known as Atrogin 1 or MAFbx, is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif F-box. This protein is an E3 ubiquitin ligase that is markedly up-regulated in muscle atrophy. FBXO32 is thus a potential drug target for the treatment of muscle atrophy. Some data support that FBXO32 may play an important role in tumorigenesis. Recent study reveal that FBXO32 targets the oncogenic protein c-Myc for ubiquitination and degradation through the proteasome pathway.