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FcRn-Specific Polyclonal antibody
FcRn-Specific Polyclonal Antibody for WB, IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (2)
Applications
WB, IHC, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | THP-1 cells, human placenta tissue, human liver tissue |
Positive IHC detected in | human spleen tissue, human liver tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:1000 |
Immunohistochemistry (IHC) | IHC : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
16190-1-AP targets FcRn-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IHC, ELISA Application Description |
Cited Applications | WB, IF |
Tested Reactivity | human |
Cited Reactivity | human, pig, canine |
Immunogen | Peptide 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | Fc fragment of IgG, receptor, transporter, alpha |
Synonyms | alpha chain, FCGRT, FCRN, FcRn-Specific, Neonatal Fc receptor |
Calculated Molecular Weight | 40 kDa |
Observed Molecular Weight | 35-40 kDa |
GenBank Accession Number | NM_004107 |
Gene Symbol | FcRn |
Gene ID (NCBI) | 2217 |
RRID | AB_2231751 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P55899 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
实验方案
Product Specific Protocols | |
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WB protocol for FcRn-Specific antibody 16190-1-AP | Download protocol |
IHC protocol for FcRn-Specific antibody 16190-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Cell Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
| ||
Front Immunol Impact of mAb-FcRn affinity on IgG transcytosis across human well-differentiated airway epithelium | ||
Clin Dev Immunol Human antibodies can cross guinea pig placenta and bind its neonatal Fc Receptor: implications for studying immune prophylaxis and therapy during pregnancy. | ||
Placenta Gestation age dependent transfer of human immunoglobulins across placenta in timed-pregnant guinea pigs. | ||
Int J Mol Sci Recombinant Humanized IgG1 Antibody Promotes Reverse Cholesterol Transport through FcRn-ERK1/2-PPARα Pathway in Hepatocytes | ||
J Agric Food Chem Prevention of Hypercholesterolemia with "Liposomes in Microspheres" Composite Carriers: A Promising Approach for Intestinal-Targeted Oral Delivery of Astaxanthin |