验证数据展示
产品信息
60341-1-PBS targets FGF18 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rabbit samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rabbit |
| 免疫原 | FGF18 fusion protein Ag2041 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | fibroblast growth factor 18 |
| 别名 | FGF 18, FGF18, fibroblast growth factor 18, ZFGF5 |
| 计算分子量 | 207 aa, 24 kDa |
| 观测分子量 | 21 kDa |
| GenBank蛋白编号 | BC006245 |
| 基因名称 | FGF18 |
| Gene ID (NCBI) | 8817 |
| RRID | AB_2881450 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O76093 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
