FGFR1 Monoclonal antibody, PBS Only (Detector)

FGFR1 Monoclonal Antibody for WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgG2c

Reactivity

human

Applications

WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

10F12E7

Cat no : 60325-1-PBS

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Synonyms

EC:2.7.10.1, CEK, CD331, bFGF-R-1, BFGFR



产品信息

60325-1-PBS targets FGFR1 as part of a matched antibody pair:

MP50453-3: 68982-1-PBS capture and 60325-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen FGFR1 fusion protein Ag3646 种属同源性预测
Host / Isotype Mouse / IgG2c
Class Monoclonal
Type Antibody
Full Name fibroblast growth factor receptor 1
Synonyms EC:2.7.10.1, CEK, CD331, bFGF-R-1, BFGFR
Calculated Molecular Weight 820 aa, 91 kDa
Observed Molecular Weight 91 kDa
GenBank Accession NumberBC018128
Gene Symbol FGFR1
Gene ID (NCBI) 2260
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP11362
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processes including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in the FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer, and autosomal dominant Kallmann syndrome. Alternatively spliced variants that encode different protein isoforms have been described.