• Featured Product
  • KD/KO Validated

Fibrinogen Gamma Chain Polyclonal antibody

Fibrinogen Gamma Chain Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA and More (1)

Conjugate

Unconjugated

Cat no : 15841-1-AP

Print datasheet

Synonyms

FGG, PRO2061



经过测试的应用

Positive WB detected inHepG2 cells, human liver tissue, human spleen tissue, mouse liver tissue, mouse spleen tissue, rat spleen tissue
Positive IHC detected inhuman hepatocirrhosis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunohistochemistry (IHC)IHC : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

15841-1-AP targets Fibrinogen Gamma Chain in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, ELISA Application Description
Cited ApplicationsWB, IHC, IF
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Immunogen Fibrinogen Gamma Chain fusion protein Ag8597 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name fibrinogen gamma chain
Synonyms FGG, PRO2061
Calculated Molecular Weight453aa,52 kDa; 437aa,50 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC007044
Gene Symbol Fibrinogen Gamma Chain
Gene ID (NCBI) 2266
RRIDAB_2103801
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP02679
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGG is the gamma chain of fibrinogen. Mutations in the gene of FGG lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.

实验方案

Product Specific Protocols
WB protocol for Fibrinogen Gamma Chain antibody 15841-1-APDownload protocol
IHC protocol for Fibrinogen Gamma Chain antibody 15841-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
human,ratIHC,IF

Blood

Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.

Authors - Krishnamoorthy Aparna A
mouse

J Thromb Haemost

Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) cross-linking via tissue transglutaminase.

Authors - L G Poole
humanWB

Sci Rep

C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.

Authors - Anika Alberts
ratIHC

J Neurotrauma

FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model.

Authors - Kazuyoshi Yamazaki
humanWB,IHC,IF

Front Neurosci

Fibrinogen Chains Intrinsic to the Brain.

Authors - Eugene V Golanov
  • KD Validated
mouseIHC

Cell Mol Neurobiol

Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.

Authors - Fei Yao