FHIT Monoclonal antibody
FHIT Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
ELISA and More (2)
Conjugate
Unconjugated
CloneNo.
4D6G1
验证数据展示
发表文章中的应用
| WB | See 1 publications below |
| IHC | See 2 publications below |
产品信息
66086-1-Ig targets FHIT in WB, IHC, ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB, IHC |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Immunogen | FHIT fusion protein Ag14471 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | fragile histidine triad gene |
| Synonyms | AP3A hydrolase, AP3Aase, Bis(5 adenosyl) triphosphatase, Dinucleosidetriphosphatase, FHIT, FRA3B, fragile histidine triad gene |
| Calculated Molecular Weight | 147 aa, 17 kDa |
| Observed Molecular Weight | 17 kDa |
| GenBank Accession Number | BC032336 |
| Gene Symbol | FHIT |
| Gene ID (NCBI) | 2272 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P49789 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The candidate tumor suppressor gene, FHIT(Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5'''-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity(PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for FHIT antibody 66086-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Cancer Biomark FHIT and C-MYC expression in cervical histology and cytology as biomarkers for detecting high-grade intraepithelial neoplasia in human papillomavirus-positive women. | ||
Int J Clin Exp Pathol Upregulation of FHIT gene expression in endometrial carcinoma by RNA activation. |
