FIG4 Polyclonal antibody

FIG4 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 28499-1-AP

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Synonyms

KIAA0274, hSac3, FIG4 homolog (S. cerevisiae), EC:3.1.3.16, EC:3.1.3.-



经过测试的应用

Positive WB detected inHEK-293 cells, NIH/3T3 cells, C6 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28499-1-AP targets FIG4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen FIG4 fusion protein Ag28971 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name FIG4 homolog (S. cerevisiae)
Synonyms KIAA0274, hSac3, FIG4 homolog (S. cerevisiae), EC:3.1.3.16, EC:3.1.3.-
Calculated Molecular Weight 907 aa, 104 kDa
Observed Molecular Weight100 kDa
GenBank Accession NumberBC041338
Gene Symbol FIG4
Gene ID (NCBI) 9896
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ92562
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FIG4 (also named SAC3) is a 5'-phosphoinositide phosphatase that coordinates the turnover of phosphatidylinositol-3,5-bisphosphate (PI(3,5)P2), a very low abundance phosphoinositide. Deficiency of FIG4 severely affects the human and mouse nervous systems by causing two distinct forms of abnormal lysosomal storage (PMID: 23165282).

实验方案

Product Specific Protocols
WB protocol for FIG4 antibody 28499-1-APDownload protocol
Standard Protocols
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