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FKBP2 Recombinant antibody, PBS Only

FKBP2 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241166B9

Cat no : 84077-6-PBS

Print datasheet

Synonyms

FKBP 2, FKBP 13, FK506-binding protein 2, EC:5.2.1.8, 241166B9

验证数据展示

  • WB analysis using 84077-6-RR (same clone as 84077-6-PBS)

    WB analysis using 84077-6-RR (same clone as 84077-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84077-6-RR (FKBP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84077-6-RR

    Affinity and Kinetic Characterization of 84077-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84077-6-RR against Human FKBP2 were performed. The affinity constant is below 1 pM.

产品信息

84077-6-PBS targets FKBP2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen FKBP2 fusion protein Ag2255 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name FK506 binding protein 2, 13kDa
Synonyms FKBP 2, FKBP 13, FK506-binding protein 2, EC:5.2.1.8, 241166B9
Calculated Molecular Weight 142 aa, 16 kDa
Observed Molecular Weight 13-16 kDa
GenBank Accession NumberBC003384
Gene Symbol FKBP2
Gene ID (NCBI) 2286
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP26885
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FKBP2 is also named as FKBP13 and belongs to the FKBP-type PPIase family. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP2 has a 21-amino acid signal peptide and appears to be membrane-associated(PMID:1713687). It is localized to the lumen of the endoplasmic reticulum (ER). FKBP12 and FKBP13 are highly similar proteins, of molecular masses 12 kDa and 13 kDa respectively, with approx.43 % amino acid identity. The strong homology between FKBP12 and FKBP13 suggests that they may share similar biological functions, although, apart from rotamase activity, details relating to the function of either protein are scant (PMID:8373365).