VEGFR3/FLT4 Polyclonal antibody

VEGFR3/FLT4 Polyclonal Antibody for WB, ELISA
Cat No. 20712-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse and More (1)

应用

WB, ELISA and More (2)

FLT4, Fms like tyrosine kinase 4, FLT41, FLT-4, FLT 4

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse spleen tissue, PC-3 cells, HeLa cells, mouse heart tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

20712-1-AP targets VEGFR3/FLT4 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human, mouse
文献引用反应性human, mouse, deer
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 fms-related tyrosine kinase 4
别名 FLT4, Fms like tyrosine kinase 4, FLT41, FLT-4, FLT 4
计算分子量 153 kDa
观测分子量 125 kDa
GenBank蛋白编号NM_002020
基因名称 FLT4
Gene ID (NCBI) 2324
RRIDAB_10733474
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP35916
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FLT4, also named VEGFR-3, belongs to the protein kinase superfamily, Tyr protein kinase family, and CSF-1/PDGF receptor subfamily. It is a receptor for VEGFC. FLT4 has a tyrosine-protein kinase activity. Defects in FLT4 cause lymphedema hereditary type 1 (LYH1A). Defects in FLT4 are found in juvenile hemangioma. VEGFR-3 is a highly glycosylated protein and migrates as bands with different molecular weights: an ~175 kDa precursor, an ~195 kDa mature form, an ~140 kDa non-glycosylated backbone, and a form that appears to be partially cleaved proteolytically in the extracellular domain to produce an ~125 kDa band(PMID: 15389531).

实验方案

Product Specific Protocols
WB protocol for VEGFR3/FLT4 antibody 20712-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIF

Mol Cancer

m6A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma

Authors - Han Fang
humanIHC

Front Oncol

The Specifically Androgen-Regulated Gene (SARG) Promotes Papillary Thyroid Carcinoma (PTC) Lymphatic Metastasis Through Vascular Endothelial Growth Factor C (VEGF-C) and VEGF Receptor 3 (VEGFR-3) Axis.

Authors - Shuai-Jun Xu
DeerWB

Stem Cell Res Ther

Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.

Authors - Wei Zhang
humanWB

Pharmaceuticals (Basel)

Use of Early Donated COVID-19 Convalescent Plasma Is Optimal to Preserve the Integrity of Lymphatic Endothelial Cells.

Authors - Nada Amri
humanWB

Mol Cell Endocrinol

Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.

Authors - Zhi-You He
humanWB

Oral Dis

Linagliptin's impact on lymphatic barrier and lymphangiogenesis in oral cancer with high glucose

Authors - Hongyu Wang
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