• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

FNDC5 Recombinant antibody, PBS Only

FNDC5 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse, rat, pig

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2H3

Cat no : 82671-1-PBS

Print datasheet

Synonyms

FNDC5, FRCP2

验证数据展示

  • WB analysis using 82671-1-RR (same clone as 82671-1-PBS)

    WB analysis using 82671-1-RR (same clone as 82671-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82671-1-RR (FNDC5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82671-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse skeletal muscle using 82671-1-RR (same clone as 82671-1-PBS)

    IHC staining of mouse skeletal muscle using 82671-1-RR (same clone as 82671-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 82671-1-RR (FNDC5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 82671-1-PBS in a different storage buffer formulation.

产品信息

82671-1-PBS targets FNDC5 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, pig
Immunogen FNDC5 fusion protein Ag29714 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name fibronectin type III domain containing 5
Synonyms FNDC5, FRCP2
Calculated Molecular Weight 212 aa, 24 kDa
Observed Molecular Weight 25-30 kDa
GenBank Accession NumberBC062297
Gene Symbol FNDC5
Gene ID (NCBI) 252995
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8NAU1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

fibronectin type III domain containing 5(FNDC5) encodes 23 kDa protein, which is a membrane protein that is cleaved and secreted as a newly identified hormone, irisin. Exercise-induced FNDC5 gene expression in muscles was accompanied by a parallel increase in the concentration of circulating irisin, which in turn activates adipocyte thermogenic programs, leading to mitochondrial heat production and energy expenditure.