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验证数据展示

  • WB analysis of HEK-293 using 55365-1-AP (same clone as 55365-1-PBS)

    WB analysis of HEK-293 using 55365-1-AP (same clone as 55365-1-PBS)

    WB result of FOXC1 antibody (55365-1-AP; 1:300; incubated at room temperature for 1.5 hours) with sh-Control and sh-FOXC1 transfected HEK-293 cells. This data was developed using the same antibody clone with 55365-1-PBS in a different storage buffer formulation.

  • IP experiment of HepG2 using 55365-1-AP (same clone as 55365-1-PBS)

    IP experiment of HepG2 using 55365-1-AP (same clone as 55365-1-PBS)

    IP result of anti-FOXC1 (IP:55365-1-AP, 4ug; Detection:55365-1-AP 1:300) with HepG2 cells lysate 4000 ug. This data was developed using the same antibody clone with 55365-1-PBS in a different storage buffer formulation.

  • WB analysis of MCF-7 using 55365-1-AP (same clone as 55365-1-PBS)

    WB analysis of MCF-7 using 55365-1-AP (same clone as 55365-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 55365-1-AP (FOXC1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55365-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

FOXC1 Polyclonal antibody, PBS Only

FOXC1 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 55365-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

55365-1-PBS targets FOXC1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 forkhead box C1
别名
计算分子量 57 kDa
观测分子量 70 kDa
GenBank蛋白编号NM_001453
基因名称 FOXC1
Gene ID (NCBI) 2296
RRIDAB_2881316
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ12948
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FOXC1, also named as FKHL7 and FREAC3, binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3). Defects in FOXC1 are the cause of iridogoniodysgenesis anomaly (IGDA). Defects in FOXC1 are a cause of Peters anomaly. This antibody is specific to FOXC1. Phosphorylation modification of Foxc1 protein may be responsible for the larger molecular weight of detection compared with theoretical molecular weight (PMID:27708239;16403239).