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FOXC2 Monoclonal antibody, PBS Only

FOXC2 Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, Rat, Pig

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

3E3E1

Cat no : 68384-1-PBS

Print datasheet

Synonyms

FKHL14, Forkhead box protein C2, FOXC2, LD, Mesenchyme fork head protein 1, MFH 1, MFH 1 protein, MFH1, Transcription factor FKH 14

验证数据展示

  • IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68384-1-Ig (FOXC2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68384-1-Ig (FOXC2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

  • WB analysis of hTERT-RPE1 using 68384-1-Ig (same clone as 68384-1-PBS)

    WB analysis of hTERT-RPE1 using 68384-1-Ig (same clone as 68384-1-PBS)

    hTERT-RPE1 cells were subjected to SDS PAGE followed by western blot with 68384-1-Ig (FOXC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

  • WB analysis using 68384-1-Ig (same clone as 68384-1-PBS)

    WB analysis using 68384-1-Ig (same clone as 68384-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68384-1-Ig (FOXC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

产品信息

68384-1-PBS targets FOXC2 in WB, IHC, ELISA applications and shows reactivity with Human, Rat, Pig samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity Human, Rat, Pig
Immunogen FOXC2 fusion protein Ag19378 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name forkhead box C2 (MFH-1, mesenchyme forkhead 1)
Synonyms FKHL14, Forkhead box protein C2, FOXC2, LD, Mesenchyme fork head protein 1, MFH 1, MFH 1 protein, MFH1, Transcription factor FKH 14
Calculated Molecular Weight 501 aa, 54 kDa
Observed Molecular Weight56 kDa
GenBank Accession NumberBC113437
Gene Symbol FOXC2
Gene ID (NCBI) 2303
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ99958
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene. FOXC2 is a member of the fork head box (FOX) family of transcription factors. FOX transcription factors are expressed during development and are associated with a number of cellular and developmental differentiation processes. FOXC2 is required during early development of the kidneys, including differentiation of podocytes and maturation of the glomerular basement membrane. It is also involved in the early development of the heart. FOXC2 is also involved in cancer metastases. In particular, expression of FOXC2 is induced when epithelial cells undergo an epithelial-mesenchymal transition (EMT) and become mesenchymal looking cells. (PMID: 8674414 9169153 19935708)