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验证数据展示

  • IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68384-1-Ig (FOXC2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    IHC staining of human breast cancer using 68384-1-Ig (same clone as 68384-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68384-1-Ig (FOXC2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

  • WB analysis of hTERT-RPE1 using 68384-1-Ig (same clone as 68384-1-PBS)

    WB analysis of hTERT-RPE1 using 68384-1-Ig (same clone as 68384-1-PBS)

    hTERT-RPE1 cells were subjected to SDS PAGE followed by western blot with 68384-1-Ig (FOXC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

  • WB analysis using 68384-1-Ig (same clone as 68384-1-PBS)

    WB analysis using 68384-1-Ig (same clone as 68384-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68384-1-Ig (FOXC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68384-1-PBS in a different storage buffer formulation.

FOXC2 Monoclonal antibody, PBS Only

FOXC2 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 68384-1-PBS

产品说明书

CloneNo. 3E3E1

宿主/亚型

Mouse / IgG2b

种属反应性

Human, Rat, Pig

应用

WB, IHC, ELISA

别名

FKHL14, Forkhead box protein C2, FOXC2, LD, Mesenchyme fork head protein 1, MFH 1, MFH 1 protein, MFH1, Transcription factor FKH 14

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68384-1-PBS targets FOXC2 in WB, IHC, ELISA applications and shows reactivity with Human, Rat, Pig samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 Human, Rat, Pig
免疫原 FOXC2 fusion protein Ag19378 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 forkhead box C2 (MFH-1, mesenchyme forkhead 1)
别名 FKHL14, Forkhead box protein C2, FOXC2, LD, Mesenchyme fork head protein 1, MFH 1, MFH 1 protein, MFH1, Transcription factor FKH 14
计算分子量 501 aa, 54 kDa
观测分子量56 kDa
GenBank蛋白编号BC113437
基因名称 FOXC2
Gene ID (NCBI) 2303
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99958
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene. FOXC2 is a member of the fork head box (FOX) family of transcription factors. FOX transcription factors are expressed during development and are associated with a number of cellular and developmental differentiation processes. FOXC2 is required during early development of the kidneys, including differentiation of podocytes and maturation of the glomerular basement membrane. It is also involved in the early development of the heart. FOXC2 is also involved in cancer metastases. In particular, expression of FOXC2 is induced when epithelial cells undergo an epithelial-mesenchymal transition (EMT) and become mesenchymal looking cells. (PMID: 8674414 9169153 19935708)