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FOXP2 Polyclonal antibody

FOXP2 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, ELISA and More (3)

Conjugate

Unconjugated

Cat no : 20529-1-AP

Print datasheet

Synonyms

CAG repeat protein 44, CAGH44, forkhead box P2, Forkhead box protein P2, FOXP2, SPCH1, TNRC10



经过测试的应用

Positive WB detected inHCT 116 cells, Neuro-2a cells, mouse brain tissue, mouse lung tissue, rat brain tissue
Positive IP detected inmouse spleen tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

20529-1-AP targets FOXP2 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IP, ELISA Application Description
Cited ApplicationsWB, IHC, IF, CoIP
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, rat
Immunogen FOXP2 fusion protein Ag14391 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name forkhead box P2
Synonyms CAG repeat protein 44, CAGH44, forkhead box P2, Forkhead box protein P2, FOXP2, SPCH1, TNRC10
Calculated Molecular Weight 80 kDa
Observed Molecular Weight 70-80 kDa
GenBank Accession NumberBC018016
Gene Symbol FOXP2
Gene ID (NCBI) 93986
RRIDAB_10695756
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO15409
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FOXP2, Forkhead box protein P2, is associated with speech and language development (PMID: 24765219). FOXP2 is expressed in the brain, lungs, heart and gut. In the brain, it is widely expressed in sensory, limbic and motor structures(PMID: 10880297, PMID:15685218). Mutations in FOXP2 caused the severe speech and language disorder developmental verbal dyspraxia (PMID: 15877281). FOXP2 was detected 2 isoforms of 70 kDa and 80-82 kDa (PMID: 15056696, PMID: 29360038, PMID: 17999357).

实验方案

Product Specific Protocols
WB protocol for FOXP2 antibody 20529-1-APDownload protocol
IP protocol for FOXP2 antibody 20529-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Mol Ther Nucleic Acids

circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.

Authors - Qianru He
humanWB,IHC,IF,CoIP

J Cancer

Low expression of FOXP2 predicts poor survival and targets caspase-1 to inhibit cell pyroptosis in colorectal cancer.

Authors - Peng Liao
  • KD Validated
ratIHC

BMC Biol

GnRH-driven FTO-mediated RNA m6A modification promotes gonadotropin synthesis and secretion

Authors - Hao-Qi Wang