验证数据展示
产品信息
67131-1-PBS targets FSHB in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | FSHB fusion protein Ag13788 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | follicle stimulating hormone, beta polypeptide |
别名 | Follitropin beta chain, Follitropin subunit beta, FSH B, FSH beta, FSHB |
计算分子量 | 129 aa, 15 kDa |
GenBank蛋白编号 | BC113488 |
基因名称 | FSHB |
Gene ID (NCBI) | 2488 |
RRID | AB_2882430 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P01225 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The FSHB gene encodes the beta subunit of follicle-stimulating hormone (FSH), particularly expressed in gonadotroph cells within the anterior pituitary gland and plays a critical role in the regulation of gonadal function, pubertal maturation and reproductive processes in mammals. The transcription of the FSHB gene is critical for the production of the FSH hormone(PMID:28281143). And FSH is required for ovarian folliculogenesis in females, in males it promotes spermatogenesis in conjunction with testosterone(PMID:11739331). Mutations in FSHB gene would result in infertility both in men and women (PMID: 23766128).