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  • Featured Product
  • KD/KO Validated

FXR1 Polyclonal antibody, PBS Only

FXR1 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13194-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 13194-1-AP (same clone as 13194-1-PBS)

    WB analysis using 13194-1-AP (same clone as 13194-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13194-1-AP (FXR1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse skeletal muscle using 13194-1-AP (same clone as 13194-1-PBS)

    IP experiment of mouse skeletal muscle using 13194-1-AP (same clone as 13194-1-PBS)

    IP result of anti-FXR1 (IP:13194-1-AP, 3ug; Detection:13194-1-AP 1:800) with mouse skeletal muscle tissue lysate 8000ug. This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 13194-1-AP (same clone as 13194-1-PBS)

    IHC staining of human heart using 13194-1-AP (same clone as 13194-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart using 13194-1-AP (FXR1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FXR1 antibody included
  • IF Staining of HeLa using 13194-1-AP (same clone as 13194-1-PBS)

    IF Staining of HeLa using 13194-1-AP (same clone as 13194-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using FXR1 antibody (13194-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13194-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy FXR1 Ready-To-Use IHC Kit. FXR1 primary antibody included.

产品信息

13194-1-PBS targets FXR1 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen FXR1 fusion protein Ag3873 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name fragile X mental retardation, autosomal homolog 1
Synonyms
Calculated Molecular Weight 621 aa, 70 kDa
Observed Molecular Weight70-80 kDa
GenBank Accession NumberBC028983
Gene Symbol FXR1
Gene ID (NCBI) 8087
RRIDAB_2110702
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP51114
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tumour necrosis factor-alpha (TNF-alpha) is a key mediator of inflammation in host defence against infection and in autoimmune disease. Its production is controlled post-transcriptionally by multiple RNA-binding proteins that interact with the TNF-alpha AU-rich element and regulate its expression; Fragile X mental retardation-related protein 1 (FXR1) is one of these. FXR1 (fragile-X-mental retardation-related protein 1) are RNA-binding proteins that have been demonstrated to impact miRNA-mediated, post-transcriptional gene regulation, and required for embryonic and postnatal development of muscle tissue. It can regulate intracellular transport and local translation of certain mRNAs. The FXR1 exists some isoforms with the MW 69 kDa and 60 kDa.