验证数据展示
产品信息
84816-4-PBS targets FceR1a in WB, Indirect ELISA applications and shows reactivity with mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | mouse |
免疫原 | Recombinant protein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | Fc receptor, IgE, high affinity I, alpha polypeptide |
别名 | High affinity immunoglobulin epsilon receptor subunit alpha, Fcr 5, FcERI, FceR1, Fce1a |
计算分子量 | 29 kDa |
观测分子量 | 42 kDa |
GenBank蛋白编号 | NM_010184.2 |
基因名称 | FceR1a |
Gene ID (NCBI) | 14125 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P20489 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).