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Host
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Conjugate
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Conjugate
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验证数据展示

  • WB analysis of human plasma using 80793-1-RR (same clone as 80793-1-PBS)

    WB analysis of human plasma using 80793-1-RR (same clone as 80793-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 80793-1-RR (Fetuin-A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80793-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 80793-1-RR

    Affinity and Kinetic Characterization of 80793-1-RR

    Biolayer interferometry (BLl) kinetic assays of 80793-1-RR against Human AHSG were performed. The affinity constant is 5.52 nM.

Fetuin-A/AHSG Recombinant antibody, PBS Only

Fetuin-A/AHSG Recombinant Antibody for WB, Indirect ELISA
Cat No. 80793-1-PBS

产品说明书

CloneNo. 1E4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

AHSG, Fetuin-A, Alpha 2 Z globulin, alpha 2 HS glycoprotein, AHS

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy AHSG/Fetuin A Ready-To-Use IHC Kit. AHSG/Fetuin A primary antibody included.

产品信息

80793-1-PBS targets Fetuin-A/AHSG in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Fetuin-A/AHSG fusion protein Ag9853 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 alpha-2-HS-glycoprotein
别名 AHSG, Fetuin-A, Alpha 2 Z globulin, alpha 2 HS glycoprotein, AHS
计算分子量 367 aa, 39 kDa
观测分子量58 kDa
GenBank蛋白编号BC048198
基因名称 Fetuin-A
Gene ID (NCBI) 197
RRIDAB_2918913
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP02765
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fetuin-A, also named as Alpha2-HS glycoprotein (AHSG), is a member of cystatin superfamily of protease inhibitors. It is a highly expressed glycoprotein in various fetal tissues whereas it is mainly expressed by the liver in adults. Fetuin A, an extracellular inhibitor of transforming growth factor β, is a profibrogenic stimulus in liver disease. Circulating fetuin-A may be a beneficial serum biomarker in the detection of liver and vascular fibrosis progression in patients with non-alcoholic fatty liver disease. It is also involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Fetuin-A exerts its effects on the cardiovascular system by two different mechanisms. On the one hand it inhibits ins signaling and induces ins resistance contributing to the onset of atherosclerosis and on the other hand it inhibits calcium deposition and protects from vascular calcification.