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  • Featured Product
  • KD/KO Validated

Fibrinogen Alpha Chain Polyclonal antibody, PBS Only

Fibrinogen Alpha Chain Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 20645-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse liver using 20645-1-AP (same clone as 20645-1-PBS)

    WB analysis of mouse liver using 20645-1-AP (same clone as 20645-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 20645-1-AP (Fibrinogen alpha chain antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

    IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

    IHC staining of human colon using 20645-1-AP (same clone as 20645-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

    IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

    IHC staining of human liver cancer using 20645-1-AP (same clone as 20645-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

    IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

    IHC staining of human lung cancer using 20645-1-AP (same clone as 20645-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 20645-1-AP (Fibrinogen Alpha Chain antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20645-1-PBS in a different storage buffer formulation.

产品信息

20645-1-PBS targets Fibrinogen Alpha Chain in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen Fibrinogen Alpha Chain fusion protein Ag9567 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name fibrinogen alpha chain
Synonyms
Calculated Molecular Weight 866 aa, 95 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC020764
Gene Symbol Fibrinogen Alpha Chain
Gene ID (NCBI) 2243
RRIDAB_2878715
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP02671
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGA is the alpha chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide A is cleaved from FGA by thrombin.