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Host
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis of human heart using 66186-1-Ig (same clone as 66186-1-PBS)

    WB analysis of human heart using 66186-1-Ig (same clone as 66186-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66186-1-PBS in a different storage buffer formulation.

Fibrinogen Beta Chain Monoclonal antibody, PBS Only

Fibrinogen Beta Chain Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66186-1-PBS

产品说明书

CloneNo. 1F8E4

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, Indirect ELISA

别名

FGB, fibrinogen beta chain

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy FGB Ready-To-Use IHC Kit. FGB primary antibody included.

产品信息

66186-1-PBS targets Fibrinogen Beta Chain in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Fibrinogen Beta Chain fusion protein Ag10205 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 fibrinogen beta chain
别名 FGB, fibrinogen beta chain
计算分子量 491 aa, 56 kDa
观测分子量 50 kDa
GenBank蛋白编号BC107766
基因名称 Fibrinogen Beta Chain
Gene ID (NCBI) 2244
RRIDAB_2881581
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP02675
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGB is the beta chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide B is cleaved from FGB by thrombin. Mutations in the gene of FGB lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.