G3BP1 Recombinant antibody, PBS Only

G3BP1 Uni-rAbTM Recombinant Antibody for IHC, IF/ICC, IF-P, Indirect ELISA
Cat No. 80777-1-PBS

产品说明书

CloneNo. 7F14

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF/ICC, IF-P, Indirect ELISA

7F14, ATP-dependent DNA helicase VIII, EC:3.6.4.12, G3BP, G3BP 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy G3BP1 Ready-To-Use IHC Kit. G3BP1 primary antibody included.

产品信息

80777-1-PBS targets G3BP1 in IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF/ICC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 G3BP1 fusion protein Ag3728 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 GTPase activating protein (SH3 domain) binding protein 1
别名 7F14, ATP-dependent DNA helicase VIII, EC:3.6.4.12, G3BP, G3BP 1
计算分子量 466 aa, 52 kDa
GenBank蛋白编号BC006997
基因名称 G3BP1
Gene ID (NCBI) 10146
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13283
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GAP SH3 Binding Protein 1 (G3BP1), also named as G3BP, is an effector of stress granule (SG) assembly. SG biology plays an important role in the pathophysiology of TDP-43 in ALS and FTLD-U. G3BP1 can be used as a marker of SG. It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is a ubiquitously expressed protein that localizes to the cytoplasm in proliferating cells and to the nucleus in non-proliferating cells. G3BP1 has recently been implicated in cancer biology.

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