G3BP1 Recombinant antibody, PBS Only
G3BP1 Recombinant Antibody for Indirect ELISA,IF
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
Indirect ELISA,IF
Conjugate
Unconjugated
CloneNo.
7F14
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy G3BP1 Ready-To-Use IHC Kit. G3BP1 primary antibody included.
产品信息
80777-1-PBS targets G3BP1 in IF, Indirect ELISA applications and shows reactivity with Human samples.
Tested Applications | Indirect ELISA,IF Application Description |
Tested Reactivity | Human |
Immunogen | G3BP1 fusion protein Ag3728 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | GTPase activating protein (SH3 domain) binding protein 1 |
Synonyms | G3BP, G3BP 1, G3BP1, HDH VIII |
Calculated Molecular Weight | 466 aa, 52 kDa |
GenBank Accession Number | BC006997 |
Gene Symbol | G3BP1 |
Gene ID (NCBI) | 10146 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q13283 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
背景介绍
GAP SH3 Binding Protein 1 (G3BP1), also named as G3BP, is an effector of stress granule (SG) assembly. SG biology plays an important role in the pathophysiology of TDP-43 in ALS and FTLD-U. G3BP1 can be used as a marker of SG. It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is a ubiquitously expressed protein that localizes to the cytoplasm in proliferating cells and to the nucleus in non-proliferating cells. G3BP1 has recently been implicated in cancer biology.