GABRG2 Monoclonal antibody
GABRG2 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse, rat, rabbit
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
1H10E1
验证数据展示
经过测试的应用
| Positive WB detected in | rabbit brain tissue, rat brain tissue, mouse brain tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
68595-1-Ig targets GABRG2 in WB, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.
| Tested Applications | WB, ELISA Application Description |
| Tested Reactivity | human, mouse, rat, rabbit |
| Immunogen | GABRG2 fusion protein Ag5489 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
| Synonyms | GABAAR subunit gamma-2, GABA(A) receptor subunit gamma-2, GABA A receptor gamma 2, ECA2, CAE2 |
| Calculated Molecular Weight | 467 aa, 54 kDa |
| Observed Molecular Weight | 40-54 kDa |
| GenBank Accession Number | BC059389 |
| Gene Symbol | GABRG2 |
| Gene ID (NCBI) | 2566 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P18507 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2), which is expected to be located in cell membrane and expressed in brain and retina. The calculated molecular weight of the protein is 54 kDa. This antibody can recognize the 43 kDa band of target (PMID:12091434). And it also has glycosylation modification. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for GABRG2 antibody 68595-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |