验证数据展示
经过测试的应用
Positive WB detected in | mouse brain tissue, mouse skeletal muscle tissue |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
25899-1-AP targets GABRR1 in WB, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, ELISA Application Description |
文献引用应用 | WB, IF, IP, CoIP |
经测试反应性 | human, mouse |
文献引用反应性 | mouse |
免疫原 | GABRR1 fusion protein Ag23165 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | gamma-aminobutyric acid (GABA) receptor, rho 1 |
别名 | GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1 |
计算分子量 | 479 aa, 56 kDa |
观测分子量 | 50-56 kDa |
GenBank蛋白编号 | BC130344 |
基因名称 | GABRR1 |
Gene ID (NCBI) | 2569 |
RRID | AB_2880290 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P24046 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.
实验方案
Product Specific Protocols | |
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WB protocol for GABRR1 antibody 25899-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
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Insect Sci Rho 1 participates in parasitoid wasp eggs maturation and host cellular immunity inhibition | ||
Biochem Biophys Res Commun Extraction method combining saponin and trehalose useful for analyzing fragile intermolecular association | ||
Transl Psychiatry Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice |