GABRR1 Polyclonal antibody

GABRR1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA and More (3)

Conjugate

Unconjugated

Cat no : 25899-1-AP

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Synonyms

GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1



经过测试的应用

Positive WB detected inmouse brain tissue, mouse skeletal muscle tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

25899-1-AP targets GABRR1 in WB, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF, IP, CoIP
Tested Reactivity human, mouse
Cited Reactivitymouse
Immunogen GABRR1 fusion protein Ag23165 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name gamma-aminobutyric acid (GABA) receptor, rho 1
Synonyms GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1
Calculated Molecular Weight 479 aa, 56 kDa
Observed Molecular Weight 50-56 kDa
GenBank Accession NumberBC130344
Gene Symbol GABRR1
Gene ID (NCBI) 2569
RRIDAB_2880290
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP24046
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.

实验方案

Product Specific Protocols
WB protocol for GABRR1 antibody 25899-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
IF

Insect Sci

Rho 1 participates in parasitoid wasp eggs maturation and host cellular immunity inhibition

Authors - Ruijuan Wang
mouseWB,IP,CoIP

Biochem Biophys Res Commun

Extraction method combining saponin and trehalose useful for analyzing fragile intermolecular association

Authors - Takahiro Fujimoto
mouseWB

Transl Psychiatry

Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

Authors - Kyosuke Yamanishi