验证数据展示
产品信息
13671-1-PBS targets GALNT6 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | GALNT6 fusion protein Ag4652 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) |
别名 | pp GaNTase 6, Polypeptide N-acetylgalactosaminyltransferase 6, GalNAc-T6, GalNAcT6, GALNAC T6 |
计算分子量 | 622 aa, 71 kDa |
观测分子量 | 71 kDa |
GenBank蛋白编号 | BC035822 |
基因名称 | GALNT6 |
Gene ID (NCBI) | 11226 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q8NCL4 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GALNT6 (polypeptide N-acetylgalactosaminyltransferase 6, GalNAc-T6), which is involved in the initiation of O-glycosylation, has been reported to play crucial roles in mammary carcinogenesis through binding to several substrates (PMID: 32393740). GALNT6 is upregulated in breast, ovarian, renal cell, lung and pancreatic cancers (PMID: 20215525). Overexpression of GRP78 could enhance Golgi-to-ER relocation of GALNT6 (PMID: 28110670).