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GBA2 Polyclonal antibody

GBA2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 17164-1-AP

Print datasheet

Synonyms

AD035, Beta glucocerebrosidase 2, Beta glucosidase 2, GBA2, Glucosylceramidase 2, KIAA1605, NLGase

验证数据展示

  • WB analysis using 17164-1-AP

    WB analysis using 17164-1-AP

    Human placenta tissue were subjected to SDS PAGE followed by western blot with 17164-1-AP (GBA2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inhuman placenta tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17164-1-AP targets GBA2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen GBA2 fusion protein Ag10606 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name glucosidase, beta (bile acid) 2
Synonyms AD035, Beta glucocerebrosidase 2, Beta glucosidase 2, GBA2, Glucosylceramidase 2, KIAA1605, NLGase
Calculated Molecular Weight 927 aa, 105 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC011363
Gene Symbol GBA2
Gene ID (NCBI) 57704
RRIDAB_2109077
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9HCG7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GBA2(Non-lysosomal glucosylceramidase) is also named as KIAA1605,NLGase and belongs to the non-lysosomal glucosylceramidase family.It catalyzes the conversion of glucosylceramide to free glucose and ceramide and is involved in sphingomyelin generation and prevention of glycolipid accumulation.GBA2 contains a putative membrane-spanning domain and 2 potential N-glycosylation sites. However, glycosidase treatment indicated that GBA2 is not a glycoprotein(PMID:11489889).It has 3 isoforms produced by alternative splicing.

实验方案

Product Specific Protocols
WB protocol for GBA2 antibody 17164-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols