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  • 概述
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GCS1 Polyclonal antibody, PBS Only

GCS1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17859-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 17859-1-AP (same clone as 17859-1-PBS)

    WB analysis using 17859-1-AP (same clone as 17859-1-PBS)

    mouse colon tissue were subjected to SDS PAGE followed by western blot with 17859-1-AP (GCS1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

  • WB analysis of COLO 320 using 17859-1-AP (same clone as 17859-1-PBS)

    WB analysis of COLO 320 using 17859-1-AP (same clone as 17859-1-PBS)

    COLO 320 cells were subjected to SDS PAGE followed by western blot with 17859-1-AP (GCS1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine using 17859-1-AP (GCS1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine using 17859-1-AP (GCS1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

产品信息

17859-1-PBS targets GCS1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen GCS1 fusion protein Ag12321 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name mannosyl-oligosaccharide glucosidase
Synonyms
Calculated Molecular Weight 837 aa, 92 kDa
Observed Molecular Weight 80-92 kDa
GenBank Accession NumberBC028337
Gene Symbol GCS1
Gene ID (NCBI) 7841
RRIDAB_10694270
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13724
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MOGS (Mannosyl-oligosaccharide glucosidase), also known as GCS1, is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor (PMID: 38187061). The resulting Glc(2)-Man(9)-GlcNAc(2) intermediate is then further modified by glucosidase II and several ER- and Golgi-resident mannosidases and glycosyltransferases, finally yielding a complex array of glycan structures (PMID: 3896128). MOGS has two isoforms, and it is located in the lumen of the endoplasmic reticulum.