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验证数据展示

  • WB analysis using 17859-1-AP (same clone as 17859-1-PBS)

    WB analysis using 17859-1-AP (same clone as 17859-1-PBS)

    mouse colon tissue were subjected to SDS PAGE followed by western blot with 17859-1-AP (GCS1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

  • WB analysis of COLO 320 using 17859-1-AP (same clone as 17859-1-PBS)

    WB analysis of COLO 320 using 17859-1-AP (same clone as 17859-1-PBS)

    COLO 320 cells were subjected to SDS PAGE followed by western blot with 17859-1-AP (GCS1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine using 17859-1-AP (GCS1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    IHC staining of human small intestine using 17859-1-AP (same clone as 17859-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine using 17859-1-AP (GCS1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17859-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

GCS1 Polyclonal antibody, PBS Only

GCS1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 17859-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

17859-1-PBS targets GCS1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 GCS1 fusion protein Ag12321 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 mannosyl-oligosaccharide glucosidase
别名
计算分子量 837 aa, 92 kDa
观测分子量 80-92 kDa
GenBank蛋白编号BC028337
基因名称 GCS1
Gene ID (NCBI) 7841
RRIDAB_10694270
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13724
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MOGS (Mannosyl-oligosaccharide glucosidase), also known as GCS1, is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor (PMID: 38187061). The resulting Glc(2)-Man(9)-GlcNAc(2) intermediate is then further modified by glucosidase II and several ER- and Golgi-resident mannosidases and glycosyltransferases, finally yielding a complex array of glycan structures (PMID: 3896128). MOGS has two isoforms, and it is located in the lumen of the endoplasmic reticulum.