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验证数据展示

  • WB analysis using 19142-1-AP (same clone as 19142-1-PBS)

    WB analysis using 19142-1-AP (same clone as 19142-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 19142-1-AP (GDF8/Myostatin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19142-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse heart using 19142-1-AP (same clone as 19142-1-PBS)

    WB analysis of mouse heart using 19142-1-AP (same clone as 19142-1-PBS)

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 19142-1-AP (GDF8/Myostatin antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19142-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 19142-1-AP (same clone as 19142-1-PBS)

    IHC staining of human heart using 19142-1-AP (same clone as 19142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 19142-1-AP (GDF8/Myostatin antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 19142-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 19142-1-AP (same clone as 19142-1-PBS)

    IHC staining of human heart using 19142-1-AP (same clone as 19142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 19142-1-AP (GDF8/Myostatin antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 19142-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 19142-1-AP (same clone as 19142-1-PBS)

    IHC staining of mouse brain using 19142-1-AP (same clone as 19142-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 19142-1-AP (GDF8/Myostatin antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19142-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

GDF8/Myostatin Polyclonal antibody, PBS Only

GDF8/Myostatin Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 19142-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

19142-1-PBS targets GDF8/Myostatin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 GDF8/Myostatin fusion protein Ag13605 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 myostatin
别名
计算分子量 375 aa, 43 kDa
观测分子量 50 and 35 kDa
GenBank蛋白编号BC074757
基因名称 MSTN
Gene ID (NCBI) 2660
RRIDAB_10638615
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO14793
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Myostatin, also known as GDF-8, is a member of the TGF-beta superfamily. Myostatin is expressed in the myotome and developing skeletal muscles. Myostatin negatively regulates skeletal muscle growth and development through the regulation of anabolic and catabolic pathways in skeletal muscles. Myostatin immunoreactive bands could be identified at ∼50, 32-35, and 16 kDa, which correspond to the precursor, glycosylated dimmer, and monomer, respectively (PMID: 17711997).