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GDNF Recombinant antibody

GDNF Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

230358G6

Cat No : 83087-2-RR

Print datasheet

Synonyms

ATF, ATF1, ATF2, GDNF, HFB1 GDNF, hGDNF

验证数据展示

  • WB analysis of mouse brain using 83087-2-RR

    WB analysis of mouse brain using 83087-2-RR

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 83087-2-RR (GDNF antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  • Affinity experiments of 83087-2-RR

    Affinity experiments of 83087-2-RR

    Biolayer interferometry (BLl) kinetic assays of 83087-2-RR against Human GDNF were performed. The affinity constant is below 1 pM.

经过测试的应用

Positive WB detected inmouse brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 83087-2-RR is GDNF Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human, Mouse
Immunogen GDNF fusion protein Ag24068 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name glial cell derived neurotrophic factor
Synonyms ATF, ATF1, ATF2, GDNF, HFB1 GDNF, hGDNF
Calculated Molecular Weight 211 aa, 24 kDa
Observed Molecular Weight 24-30 kDa
GenBank Accession NumberBC069369
Gene Symbol GDNF
Gene ID (NCBI) 2668
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP39905
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Glial-derived neurotrophic factor (GDNF) is a member of the transforming growth factor (TGF)-α family and exhibits potent neuroprotective activity. GDNF is a potent promoter of neuronal survival in the CNS and peripheral nervous system (PNS). It has a relatively high speciicity for dopaminergic neurons and thus become an efective treatment for Parkinson's diseases (PD), with clinical trials currently in progress.

实验方案

Product Specific Protocols
WB protocol for GDNF antibody 83087-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols