- Featured Product
- KD/KO Validated
GEFT Polyclonal antibody, PBS Only
GEFT Polyclonal Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
51004-1-PBS targets GEFT in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | Peptide 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | RhoA/RAC/CDC42 exchange factor |
Synonyms | |
Calculated Molecular Weight | 64 kDa |
Observed Molecular Weight | 70 kDa |
GenBank Accession Number | BC047559 |
Gene Symbol | GEFT |
Gene ID (NCBI) | 115557 |
RRID | AB_2089321 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q86VW2 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GEFT, also named as p63RhoGEF, may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis. GEFT is expressed as three isoforms (64, 53 and 68kDa).