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GFRA2 Polyclonal antibody, PBS Only

GFRA2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 55038-1-PBS

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Synonyms

验证数据展示

  • WB analysis of human placenta using 55038-1-AP (same clone as 55038-1-PBS)

    WB analysis of human placenta using 55038-1-AP (same clone as 55038-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 55038-1-AP (GFRA2 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55038-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 55038-1-AP (same clone as 55038-1-PBS)

    IHC staining of human lung cancer using 55038-1-AP (same clone as 55038-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 55038-1-AP (GFRA2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55038-1-PBS in a different storage buffer formulation.

产品信息

55038-1-PBS targets GFRA2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name GDNF family receptor alpha 2
Synonyms
Calculated Molecular Weight 52 kDa
Observed Molecular Weight 41-45 kDa
GenBank Accession NumberNM_001495
Gene Symbol GFRA2
Gene ID (NCBI) 2675
RRIDAB_10859940
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO00451
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GFRA2, also named as GDNFRB, RETL2 and TRNR2, belongs to the GDNFR family. It is a receptor for neurturin. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It is a potent survival factor for central dopaminergic neurons, motor neurons, and several other populations of neurons in the central and peripheral nervous systems. The GDNF signal is mediated by a complex of the receptor tyrosine kinase RET and a glycosylphosphatidylinositol (GPI)-linked protein, GDNFRA. GFRA2 has three isoforms with MW 34-36 kDa, 39-41 kDa and 50-52 kDa. This antibody is specific to GFRA2.