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验证数据展示

  • WB analysis of human placenta using 55038-1-AP (same clone as 55038-1-PBS)

    WB analysis of human placenta using 55038-1-AP (same clone as 55038-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 55038-1-AP (GFRA2 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55038-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 55038-1-AP (same clone as 55038-1-PBS)

    IHC staining of human lung cancer using 55038-1-AP (same clone as 55038-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 55038-1-AP (GFRA2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55038-1-PBS in a different storage buffer formulation.

GFRA2 Polyclonal antibody, PBS Only

GFRA2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 55038-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

55038-1-PBS targets GFRA2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 GDNF family receptor alpha 2
别名
计算分子量 52 kDa
观测分子量 41-45 kDa
GenBank蛋白编号NM_001495
基因名称 GFRA2
Gene ID (NCBI) 2675
RRIDAB_10859940
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO00451
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GFRA2, also named as GDNFRB, RETL2 and TRNR2, belongs to the GDNFR family. It is a receptor for neurturin. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It is a potent survival factor for central dopaminergic neurons, motor neurons, and several other populations of neurons in the central and peripheral nervous systems. The GDNF signal is mediated by a complex of the receptor tyrosine kinase RET and a glycosylphosphatidylinositol (GPI)-linked protein, GDNFRA. GFRA2 has three isoforms with MW 34-36 kDa, 39-41 kDa and 50-52 kDa. This antibody is specific to GFRA2.