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验证数据展示

  • WB analysis using 17537-1-AP

    WB analysis using 17537-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 17537-1-AP (GGTLC1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

  • IF Staining of HepG2 using 17537-1-AP

    IF Staining of HepG2 using 17537-1-AP

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using GGTLC1 antibody (17537-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red).

GGTLC1 Polyclonal antibody

GGTLC1 Polyclonal Antibody for WB, IF/ICC, ELISA
Cat No. 17537-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, ELISA

别名

GGTL6, GGTLA3, GGTLA4, GGTLC1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inHepG2 cells, L02 cells, human urine
Positive IF/ICC detected inHepG2 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17537-1-AP targets GGTLC1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human
免疫原 GGTLC1 fusion protein Ag11592 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gamma-glutamyltransferase light chain 1
别名 GGTL6, GGTLA3, GGTLA4, GGTLC1
计算分子量 225 aa, 24 kDa
观测分子量24 kDa
GenBank蛋白编号BC040904
基因名称 GGTLC1
Gene ID (NCBI) 92086
RRIDAB_3669277
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BX51
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).

实验方案

Product Specific Protocols
WB protocol for GGTLC1 antibody 17537-1-APDownload protocol
IF protocol for GGTLC1 antibody 17537-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols