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验证数据展示

  • IHC staining of mouse kidney using 17774-1-AP

    IHC staining of mouse kidney using 17774-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse kidney using 17774-1-AP

    IHC staining of mouse kidney using 17774-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse kidney using 17774-1-AP

    IHC staining of mouse kidney using 17774-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse kidney using 17774-1-AP

    IHC staining of mouse kidney using 17774-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Featured Product
  • KD/KO验证

GPR126 Polyclonal antibody

GPR126 Polyclonal Antibody for IHC, ELISA
Cat No. 17774-1-AP

产品说明书

引用文献(1)

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, ELISA and More (1)

别名

ADGRG6, APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inmouse kidney tissue, mouse lung tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17774-1-AP targets GPR126 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, ELISA Application Description
文献引用应用WB, IHC
经测试反应性 human, mouse, rat
文献引用反应性human
免疫原 GPR126 fusion protein Ag12195 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 126
别名 ADGRG6, APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR
计算分子量 1222 aa, 137 kDa
GenBank蛋白编号BC075798
基因名称 GPR126
Gene ID (NCBI) 57211
RRIDAB_2878439
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86SQ4
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GPR126 (G protein-coupled receptor 126) is a member of the adhesion GPCR family. GPR126 is all widely expressed on stromal cells (PMID: 25713288). It is essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PMID: 24227709). GPR126 regulates neural, cardiac and ear development by G-protein- and/or N-terminus-dependent signaling (PMID: 24082093, PMID: 24067352). GPR126 also stimulates VEGF signaling and angiogenesis by modulating VEGF receptor 2 expression through STAT5 and GATA2 in endothelial cells.

实验方案

Product Specific Protocols
IHC protocol for GPR126 antibody 17774-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IHC

Proc Natl Acad Sci U S A

Progesterone activates GPR126 to promote breast cancer development via the Gi pathway.

Authors - Wentao An
  • KD Validated
View Article