验证数据展示
产品信息
12659-1-PBS targets GPR155 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | GPR155 fusion protein Ag3328 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | G protein-coupled receptor 155 |
别名 | |
计算分子量 | 870 aa, 97 kDa |
观测分子量 | 97 kDa, 75 kDa |
GenBank蛋白编号 | BC028730 |
基因名称 | GPR155 |
Gene ID (NCBI) | 151556 |
RRID | AB_2877869 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q7Z3F1 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The G Protein-coupled receptor 155 (GPR155), also known as Lysosomal cholesterol signaling protein (LYCHOS), is a cholesterol receptor on the lysosome. GRR155 plays a role in the cholesterol-sensing lysosomal pathway and couples cholesterol concentration to MTORC1-dependent anabolic signaling (PMID: 36007018). GPR155 may represent a biomarker for diagnosing and predicting hematogenous metastasis of gastric cancer (PMID: 28165032).