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验证数据展示

  • WB analysis using 31846-1-AP

    WB analysis using 31846-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31846-1-AP (GPR158 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

GPR158 Polyclonal antibody

GPR158 Polyclonal Antibody for WB, ELISA
Cat No. 31846-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

Probable G-Protein Coupled Receptor 158, mGlyR, Metabotropic glycine receptor, KIAA1136, G-protein coupled receptor 158

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inHEK-293T cells, HeLa cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31846-1-AP targets GPR158 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 GPR158 fusion protein Ag34602 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 158
别名 Probable G-Protein Coupled Receptor 158, mGlyR, Metabotropic glycine receptor, KIAA1136, G-protein coupled receptor 158
计算分子量135 kDa
观测分子量150 kDa
GenBank蛋白编号BC157124
基因名称 GPR158
Gene ID (NCBI) 57512
RRIDAB_3670127
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ5T848
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

G protein-coupled receptors (GPCR) are the largest family of proteins encoded in mammalian genomes that detect extracellular signals to program cellular response, which are essential to understanding physiology, disease, and drug development (PMID: 29249361; 29298813). G protein-coupled receptor 158 (GPR158, also known as mGlyR) is a class C orphan GPCR prominently expressed in brain tissue, where it controls synapse formation and function (PMID: 22689652; 34793198). It can transduce signals by coupling to the regulator of protein signaling (RGS) proteins and be related to the development of major depressive disorder and prostate cancer (PMID: 36996198; 29419376; 25693195).

实验方案

Product Specific Protocols
WB protocol for GPR158 antibody 31846-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols