• Featured Product
  • KD/KO Validated

GPX1 Polyclonal antibody

GPX1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse, Rat and More (5)

Applications

WB, ELISA and More (1)

Conjugate

Unconjugated

Cat no : 29329-1-AP

Print datasheet

Synonyms

glutathione peroxidase 1, GPx 1, GPX1, GSHPx 1, GSHPX1



经过测试的应用

Positive WB detected inHEK-293 cells, THP-1 cells, mouse kidney tissue, rat kidney tissue, SMMC-7721 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

29329-1-AP targets GPX1 in WB, IF, ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF
Tested Reactivity Human, Mouse, Rat
Cited Reactivityhuman, mouse, rat, pig, chicken
Immunogen GPX1 fusion protein Ag31101 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name glutathione peroxidase 1
Synonyms glutathione peroxidase 1, GPx 1, GPX1, GSHPx 1, GSHPX1
Calculated Molecular Weight 22 kDa
Observed Molecular Weight22 kDa
GenBank Accession NumberBC000742
Gene Symbol GPX1
Gene ID (NCBI) 2876
RRIDAB_2918283
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP07203
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Gpx protein, known as selenoprotein, consists selenium in its catalytic site. Gpx1 is an abundant isoform, which involves in scavenging endogenous ROS using electron provided by reduced glutathione and ubiquitously expressed the cytoplasm and mitochondria of all cell types. (PMID: 30632027)

实验方案

Product Specific Protocols
WB protocol for GPX1 antibody 29329-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Mol Ther

CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.

Authors - Hao Zheng
human,mouseWB,IF

Cell Death Discov

Allicin promotes functional recovery in ischemic stroke via glutathione peroxidase-1 activation of Src-Akt-Erk

Authors - Fei Zhuang
  • KD Validated
mouseWB

Mech Ageing Dev

WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus

Authors - Jiahui Liu
mouseWB

Molecules

Polygonatum cyrtonema Hua Polysaccharides Protect BV2 Microglia Relief Oxidative Stress and Ferroptosis by Regulating NRF2/HO-1 Pathway

Authors - Jiayu Li
ratWB

Pharmaceuticals (Basel)

Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.

Authors - Pei Qian
ratWB

Acta Diabetol

Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.

Authors - Hang-Bing Dai