Glutamate receptor 3/GluA3 Polyclonal antibody

Glutamate receptor 3/GluA3 Polyclonal Antibody for WB, IF-P, IP, ELISA
Cat No. 29588-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF-P, IP, ELISA and More (1)

GRIA3, GLURC, GLUR3, GLUR K3, GLUR C

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse brain tissue, rat brain tissue
Positive IP detected inmouse brain tissue
Positive IF-P detected inrat brain tissue, mouse brain tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:6000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

29588-1-AP targets Glutamate receptor 3/GluA3 in WB, IHC, IF-P, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF-P, IP, ELISA Application Description
文献引用应用WB, IHC
经测试反应性 human, mouse, rat
文献引用反应性mouse
免疫原 Glutamate receptor 3/GluA3 fusion protein Ag30898 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glutamate receptor, ionotrophic, AMPA 3
别名 GRIA3, GLURC, GLUR3, GLUR K3, GLUR C
计算分子量 101 kDa
观测分子量101 kDa
GenBank蛋白编号NM_007325
基因名称 GRIA3
Gene ID (NCBI) 2892
RRIDAB_3086141
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP42263
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GRIA3 (Glutamate ionotropic receptor AMPA type subunit 3), also known as Glutamate receptor R3 or A3 (GluR3 or GluA3), is associated with X-linked intellectual disability (ID), dysmorphic features, and non-syndromic epilepsy(PMID: 32977175). GRIA3 also plays a role as a mediator of tumor progression in pancreatic cancer downstream CUX1(PMID: 20689760).

实验方案

Product Specific Protocols
WB protocol for Glutamate receptor 3/GluA3 antibody 29588-1-APDownload protocol
IF protocol for Glutamate receptor 3/GluA3 antibody 29588-1-APDownload protocol
IP protocol for Glutamate receptor 3/GluA3 antibody 29588-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Cell Discov

Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC

Authors - Ling-Shuang Zhu
mouseWB

Brain Res

Low-dose diazepam improves cognitive function in APP/PS1 mouse models: Involvement of AMPA receptors

Authors - Junwen Chen
mouseIHC

iScience

The decreased astrocyte-microglia interaction reflects the early characteristics of Alzheimer's disease

Authors - Kefu Liu
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