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GSDMA Polyclonal antibody

GSDMA Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 30354-1-AP

Print datasheet

Synonyms

FKSG9, FLJ39120, Gasdermin 1, gasdermin A, GSDM, GSDM1, GSDMA

验证数据展示

  • WB analysis using 30354-1-AP

    WB analysis using 30354-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 30354-1-AP (GSDMA antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inCOLO 320 cells, Daudi cells, mouse stomach tissue, mouse skin tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:14000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

30354-1-AP targets GSDMA in WB, ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human, mouse
Immunogen GSDMA fusion protein Ag31284 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name gasdermin A
Synonyms FKSG9, FLJ39120, Gasdermin 1, gasdermin A, GSDM, GSDM1, GSDMA
Calculated Molecular Weight 445 aa, 49 kDa
Observed Molecular Weight49 kDa
GenBank Accession NumberBC109197
Gene Symbol GSDMA
Gene ID (NCBI) 284110
RRIDAB_3086299
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96QA5
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.

实验方案

Product Specific Protocols
WB protocol for GSDMA antibody 30354-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols