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Guanosine 5'-triphosphate trisodium salt

Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) 是 G 蛋白 (G proteins) 信号转导活化剂。

CAS号

36051-31-7

分子式

C10H16N5Na3O14P3

主要靶点

Endogenous Metabolite

仅限科研使用

Cat No : CM00287

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Synonyms

鸟苷-5'-三磷酸三钠盐|GTP Trisodium salt|5'-GTP trisodium salt

验证数据展示

  • CAS No.: 36051-31-7

    Guanosine 5'-triphosphate trisodium salt
    CAS#: 36051-31-7

产品信息

Guanosine 5'-triphosphate trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades.Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

CAS号 36051-31-7
分子式 C10H16N5Na3O14P3
主要靶点 Endogenous Metabolite
主要通路 代谢
分子量 592.15
纯度 99.45%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 鸟苷-5'-三磷酸三钠盐|GTP Trisodium salt|5'-GTP trisodium salt

溶解度

DMSO:Insoluble,H2O:10 mM

参考文献

1.Gutkind, Silvio J . Cell growth control by G protein-coupled receptors: from signal transduction to signal integration[J]. Oncogene, 1998, 17(11):1331-1342.
2.Dhanasekaran N , Tsim S T , Dermott J M , et al. Regulation of cell proliferation by G proteins[J]. ONCOGENE, 1998, 17(11):1383-1394.
3.J Gómez, C Martínez-A, A González, et al. Dual role of Ras and Rho proteins: at the cutting edge of life and death[J]. Immunology and Cell Biology, 1998, 76(2):125-134.
4.Lacal, Carlos J . Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling[J]. Febs Letters, 1997, 410(1):73-77.
5.Schimmoller F , Simon I , Pfeffer S R . Rab GTPases, Directors of Vesicle Docking[J]. Journal of Biological Chemistry, 1998, 273(35):22161-22164.

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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