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GTSE1 Polyclonal antibody

GTSE1 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 21319-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA and More (1)

B99, G 2 and S phase expressed 1, GTSE 1, GTSE1, Protein B99 homolog

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells, SH-SY5Y cells, MCF-7 cells, mouse liver tissue, K-562 cells, L02 cells, rat liver tissue
Positive IHC detected inhuman liver cancer tissue, mouse spleen tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:8000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

21319-1-AP targets GTSE1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 GTSE1 fusion protein Ag13497 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G-2 and S-phase expressed 1
别名 B99, G 2 and S phase expressed 1, GTSE 1, GTSE1, Protein B99 homolog
计算分子量 77 kDa
观测分子量 66-77 kDa, 100 kDa
GenBank蛋白编号BC006325
基因名称 GTSE1
Gene ID (NCBI) 51512
RRIDAB_10733644
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NYZ3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

实验方案

Product Specific Protocols
WB protocol for GTSE1 antibody 21319-1-APDownload protocol
IHC protocol for GTSE1 antibody 21319-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Mod Pathol

Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets.

Authors - Ellinor Andersson
humanWB

Mol Ther Nucleic Acids

lncRNA LINC00665 Stabilized by TAF15 Impeded the Malignant Biological Behaviors of Glioma Cells via STAU1-Mediated mRNA Degradation.

Authors - Xuelei Ruan
humanIHC

Cancer Sci

High G2 and S-phase expressed 1 expression promotes acral melanoma progression and correlates with poor clinical prognosis.

Authors - Tianxiao Xu
humanWB,IHC

Lab Invest

GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.

Authors - Weihao Chen
  • KD Validated
human,mouseWB,IHC

Lab Invest

GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway.

Authors - Wenjie Lai
  • KD Validated
humanWB,IHC,IF

Mol Carcinog

G2 and S phase-expressed-1 induces chromosomal instability in esophageal squamous cell carcinoma cells and inhibits cell apoptosis through ROS/JNK signaling

Authors - Man Zhang
  • KD Validated
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