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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) 也称为 cGMP，是一种细胞调节剂，被描述为第二信使。它的水平随着各种激素的增加而增加，包括乙酰胆碱、胰岛素和催产素。 cGMP 激活蛋白激酶 G(PKG) 并调节离子通道电导，信号传导影响多种过程，包括平滑肌松弛和增殖、光转导和能量稳态。

CAS号

40732-48-7

分子式

C10H11N5NaO7P

主要靶点

PKA

仅限科研使用

Cat No : CM11475

Print datasheet

Synonyms

Monosodium-GMP|Cyclic GMP|鸟苷-3',5'-环磷酸一钠盐|cGMP sodium salt

验证数据展示

  • CAS No.: 40732-48-7

    GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD
    CAS#: 40732-48-7

产品信息

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE, also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin. cGMP activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis.

CAS号 40732-48-7
分子式 C10H11N5NaO7P
主要靶点 PKA
主要通路 蛋白酪氨酸激酶
分子量 367.19
纯度 99.44%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Monosodium-GMP|Cyclic GMP|鸟苷-3',5'-环磷酸一钠盐|cGMP sodium salt

溶解度

DMSO:12 mg/mL (32.68 mM)

参考文献

1.Hamad AM, et al. Guanylyl cyclases, nitric oxide, natriuretic peptides, and airway smooth muscle function. Am J Physiol Lung Cell Mol Physiol. 2003 Nov;285(5):L973-83.
2.Roongpraiwan R , Suthutvoravut U , Feungpean B , et al. Effect of oral vitamin E supplementation in children with cholestasis.[J]. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, 85 Suppl 4:S1199.
3.Rehim WM, et al. Antioxidant capacity in Fasciola hepatica patients before and after treatment with triclabendazole alone or in combination with ascorbic acid (vitamin C) and tocofersolan (vitamin E). Arzneimittelforschung. 2003;53(3):214-20.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2