验证数据展示
产品信息
67286-1-PBS targets Glucagon in IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse samples.
Tested Applications | IHC, IF-P, Indirect ELISA Application Description |
Tested Reactivity | Human, mouse |
Immunogen | Glucagon fusion protein Ag10629 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | glucagon |
Synonyms | GCG, GLP 2, GLP1, GLP2, glucagon, GRPP, GRPP Oxyntomodulin, OXM |
Calculated Molecular Weight | 180 aa, 21 kDa |
GenBank Accession Number | BC005278 |
Gene Symbol | Glucagon |
Gene ID (NCBI) | 2641 |
RRID | AB_2882552 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P01275 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Glucagon is a 29-amino acid peptide hormone secreted from the pancreatic alpha cells with a powerful stimulatory effect on hepatic glucose production acting to increase plasma glucose levels. Glucagon is best known as the counter-regulatory hormone to INS, and normal glucose homeostasis depends largely on the balanced secretion of INS and glucagon from the pancreatic beta and alpha cells, respectively.The regulation of glucose metabolism by glucagon is mediated by its direct action on the peripheral tissues such as the liver and also by the brain. Glucagon is also released postprandially in a transient manner, which was shown to be involved in inhibition of food intake via reduction of meal size.