验证数据展示
产品信息
67286-1-PBS targets Glucagon in IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse samples.
经测试应用 | IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | Human, mouse |
免疫原 | Glucagon fusion protein Ag10629 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | glucagon |
别名 | GCG, GLP 2, GLP1, GLP2, glucagon, GRPP, GRPP Oxyntomodulin, OXM |
计算分子量 | 180 aa, 21 kDa |
GenBank蛋白编号 | BC005278 |
基因名称 | Glucagon |
Gene ID (NCBI) | 2641 |
RRID | AB_2882552 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P01275 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Glucagon is a 29-amino acid peptide hormone secreted from the pancreatic alpha cells with a powerful stimulatory effect on hepatic glucose production acting to increase plasma glucose levels. Glucagon is best known as the counter-regulatory hormone to INS, and normal glucose homeostasis depends largely on the balanced secretion of INS and glucagon from the pancreatic beta and alpha cells, respectively.The regulation of glucose metabolism by glucagon is mediated by its direct action on the peripheral tissues such as the liver and also by the brain. Glucagon is also released postprandially in a transient manner, which was shown to be involved in inhibition of food intake via reduction of meal size.