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Host
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Species Reactivity
0
Species Reactivity
0
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0
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Compatible Species
0
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验证数据展示

  • WB analysis using 84885-4-RR (same clone as 84885-4-PBS)

    WB analysis using 84885-4-RR (same clone as 84885-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84885-4-RR (Glutamate receptor 3/GluA3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

    IHC staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84885-4-RR (Glutamate receptor 3/GluA3 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

    IHC staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84885-4-RR (Glutamate receptor 3/GluA3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

    IF Staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using Glutamate receptor 3/GluA3 antibody (84885-4-RR, Clone: 242392C11 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

Glutamate receptor 3/GluA3 Recombinant antibody, PBS Only

Glutamate receptor 3/GluA3 Uni-rAbTM Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 84885-4-PBS

产品说明书

CloneNo. 242392C11

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF-P, Indirect ELISA

别名

GRIA3, 242392C11, GluA3, GluR 3, GLUR C

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84885-4-PBS targets Glutamate receptor 3/GluA3 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Glutamate receptor 3/GluA3 fusion protein Ag30898 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 glutamate receptor, ionotrophic, AMPA 3
别名 GRIA3, 242392C11, GluA3, GluR 3, GLUR C
计算分子量 101 kDa
观测分子量 101 kDa
GenBank蛋白编号NM_007325
基因名称 GRIA3
Gene ID (NCBI) 2892
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP42263
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GRIA3 (Glutamate ionotropic receptor AMPA type subunit 3), also known as Glutamate receptor R3 or A3 (GluR3 or GluA3), is associated with X-linked intellectual disability (ID), dysmorphic features, and non-syndromic epilepsy(PMID: 32977175). GRIA3 also plays a role as a mediator of tumor progression in pancreatic cancer downstream CUX1(PMID: 20689760).